Abstract: Based on the theory of planned behavior, with entrepreneurship education and entrepreneurial self-efficacy as independent variables, entrepreneurial attitude as mediating variables, and entrepreneurial willingness as dependent variable,a model of the impact mechanism of college students’entrepreneurial willingness was constructed. 578 questionnaires were analyzed using SPSS 22.0. We found that Entrepreneurial self-efficacy has a significant positive impact on entrepreneurial attitude and entrepreneurial willingness; Entrepreneurial education has no significant effect on entrepreneurial attitude, but has a significant positive impact on college students' entrepreneurial willingness; Entrepreneurial attitude has a mediating effect in the impact of entrepreneurial self-efficacy on entrepreneurial willingness, while the mediating effect of entrepreneurial education on entrepreneurial willingness is not significant. Therefore, effective measures worth to be adopted to improve the innovation and entrepreneurship education of colleges, as well as the self-efficacy of college students, to enhance their entrepreneurial willingness.