Abstract: In the context of blended learning, learning alienation is an important factor affecting learning engagement and satisfaction, and learning support services have a significant impact on learning alienation. To explore the relationship between learning support services, learning alienation, learning engagement, and blended learning satisfaction, a survey was conducted on 417 university students using a scale of learning support services, learning alienation, learning engagement, and learning satisfaction. The results show that:(1) learning support services can directly and significantly affect learning alienation, but cannot positively and significantly affect mixed learning satisfaction through learning alienation; (2) Learning support services can directly or indirectly have a significant positive impact on blended learning satisfaction through learning engagement; (3) Learning support services can positively and significantly affect blended learning satisfaction through the chain mediating effect of learning alienation and learning engagement. Based on this, it is necessary to improve the satisfaction of blended learning by constructing a dynamic integrated learning support service system, establishing a mixed cooperative learning community, and using motivation and metacognitive strategies reasonably.